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Stroke volume

By: HWC, Views: 6645

Preload definition • Preload is the degree of stretch of cardiac muscles cells prior to contraction. • The amount of stretch is related to the end-diastolic volume[EDV]. • Increased return blood flow from the veins increases end-diastolic volume. Cardiac muscle sarcomeres stretch and ...

Second Messengers in the Inositol-lipid Signaling Pathway

By: HWC, Views: 5873

Extracellular signals produce specific responses in target cells through the action of intracellular second messengers. Here, we focus on three second messengers, IP3, DAG, and Ca2+, all involved in the inositol-lipid signaling pathway. A hormone-receptor signal on the cell surface leads to the a...

Stroke volume - contractility definition

By: HWC, Views: 6273

Contractility is the forcefulness of contraction of cardiac muscle. • Inotropic agents are substances that increase or decrease contractility (and stroke volume). • Positive inotropic agents increase contractility and will increase stroke volume and cardiac output. • Negative inotropi...

Parathyroid hormone (bone resorption) & Calcitonin (bone deposition)

By: HWC, Views: 6658

• Cellular needs for calcium may cause blood calcium concentrations to decline below the normal range. • This decrease stimulates cells in the parathyroid gland to secrete parathyroid hormone. • Binding of parathyroid hormone to osteoclasts in bone tissue promotes bone resorption and th...

Exocytosis - secretion

By: HWC, Views: 6632

Exocytosis is another method of vesicular transport that moves large volumes Of fluid or chemicals out of the cell. It is a process by which a cell transports secretory products through the cytoplasm to the plasma membrane. A examples of cellular secretory products: 1. Secreted protein - enzym...

Chemical Synapse Animation

By: HWC, Views: 4001

A neuromuscular junction is a chemical synapse between the axon endings of a motor neuron and a muscle cell. A narrow synaptic cleft separates the presynaptic cell (the motor neuron) from the postsynaptic cell (the muscle cell). The presynaptic cell contains vesicles filled with neurotransmitt...

Secondary Active Transport

By: HWC, Views: 7173

Energy stored (in a hydrogen or sodium concentration gradient) is used to drive other substances against their own concentration gradients Secondary active transport, is transport of molecules across the cell membrane utilizing energy in other forms than ATP. In many cells, antiporters mov...

Bone cells and tissues - tissue composition and cells

By: HWC, Views: 7420

Bone tissue consists of bone cells secreting bone matrix. • The extracellular bone matrix is a connective tissue that is hard, yet flexible. • Collagen fibers provide flexibility. • Inorganic mineral salts (primarily calcium phosphate, or hydroxyapatite) provide hardness. • Togethe...

Nervous pathway to the Neuromuscular (NMJ)

By: HWC, Views: 7162

• A nervous impulse, also called an action potential, starts from the brain or spinal cord to signal skeletal muscle cell contraction. Action potentials continue along a motor neuron to the muscle cell. • The signal to contract must cross a synapse - the neuromuscular junction (NMJ) - betwe...